Organization of the mucosal immunoglobulin-A system
Figure 1 Examples of interactions of epithelial cells with lymphocytes in mucosal defence. Springer Semin Immunopathol 18 : — OpenUrl CrossRef. Ann Intern Med : — Science : — Mostov KE Transepithelial transport of immunoglobulins. Annu Rev Immunol 12 : 63 — Cellular and molecular aspects. Gastroenterol Clin North Am 20 : — Protides Biol Fluids 36 : — Clin Exp Immunol 87 : 1 — 6. J Immunol : — Infect Immun 58 : — Semin Immunol 8 : 11 — Infect Immun 65 : — The anti-inflammatory effect of an oral immunoglobulin IgA-IgG preporation and its possible relevance for the prevention of necrotizing enterocolitis.
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Regulation of the formation and external transport of secretory immunoglobulins. Crit Rev Immunol ; 19 : — Cutting edge: Coordinate regulation of IFN regulatory factor-1 and the polymeric Ig receptor by proinflammatory cytokines. Immunoglobulin transport and the polymeric immunoglobulin receptor. Mucosal Immunology. Phosphorylation of the polymeric immunoglobulin recetor required for its efficient transcytosis. Science ; : — The cytoplasmic domain of the polymeric immunoglobulin receptor contains two internalization signals that are distinct from its basolateral sorting signal.
Cleavage of membrane secretory component to soluble secretory component occurs on the cell surface of rat hepatocyte monolayers. J Cell Biol ; : — Human free secretory component is composed of the first amino acid residues of the polymeric immunoglobulin receptor. FEBS Letters ; : — Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells. Calmodulin binds to the basolateral targeting signal of the polymeric immunoglobulin receptor.
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My 43, a monoclonal antibody that reacts with human myeloid cells inhibits monocyte IgA binding and triggers functions. Surface IgA and Fc-alpha receptors on human alveolar macrophages from normal subjects and from patients with sarcoidosis. Fc alpha-receptor expression on the myelomonocytic cell line THP comparison with human alveolar macrophages. Eur Respir J ; 7 : — The expression of receptors for IgA on human monocytes and calcitriol-treated HL cells.
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Characterization of the IgA receptor from human polymorphonuclear neutrophils. Immunology ; 64 : — Definition of immunoglobulin-A receptors on eosinophils and their enhanced expression in allergic individuals. J Clin Invest ; 92 : — Evidence for a specific IgA receptor in rat and human mesangial cells. The diversity of leucocyte IgA receptors. Contrib Nephrol ; : 60 — Kidney Int ; 54 : — Identification of a novel Fc alpha receptor expressed by human mesangial cells. Kidney Int ; 57 : — Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells.
J Am Soc Nephrol ; 11 : — The importance of the Fc receptors for IgA in the recognition of IgA by mouse liver cells: its comparison with carbohydrate and secretory component receptors. Immunology ; 57 : 37 — The gene for the immune IgA Fc receptor maps to 19q Hum Genet ; 89 : — Immunogen ; 43 : — Blood ; 88 : — Activation of monocytes via their Fc alpha R increases procoagulant activity.
Immunoglobulin A - an overview | ScienceDirect Topics
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A critical role for PI 3-kinase in cytokine-induced Fc alpha-receptor activation. Blood ; 95 : — Cambier JC. Antigen and Fc receptor signaling: the awesome power of the immunoreceptor tyrosine-based activation motif ITAM. Physical and functional association of Fc alpha R with tyrosine kinase Lyn. Blood ; 91 : — IgA Fc receptor CD89 activation enables coupling to syk and Btk tyrosine kinase pathways: differential signaling after IFN-gamma or phorbol ester stimulation. J Leukoc Biol ; 63 : — Immunol ; 80 : — Lipopolysaccharide and cytokine augmentation of human monocyte IgA receptor expression and function.
J Leukoc Biol ; 58 : — Influence of suramin on the expression of Fc receptors and other markers on human monocytes and U cells, and on their phagocytic properties. Immunol ; 81 : — Scand J Immunol ; 39 : — Clin Exp Immunol ; : — IgA-induced chemokinesis of human polymorphonuclear neutrophils: requirement of their Fc receptor. Mol Immunol ; 24 : — Analysis of signal transduction pathways regulating cytokine-mediated Fc receptor activation on human eosinophils.
PhosphatidylinositolOH kinase as a direct target of Ras. Inhibition of bacterial adherence by secretory immunoglobulin A: A mechanism of antigen disposal. Fisher M, Kuppers R. Eur J immunol ; 28 : — Bouvet JP, Dighiero G. Infect Immun ; 66 : 1 —4.
The immune geography of IgA induction and function
SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin-A and secretory component. Mol Microbiol ; 25 : — The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell ; : — A three-tiered view of the role of IgA in mucosal defence. Immunol Today ; 14 : — The role of IgA immunoglobulins in the passive transfer of protection to Taenia taeniaeformis in the mouse.
Immunology ; 34 : — Influence of sputum IgA and elastase on tracheal cell bacterial adherence. Cytofluorographic analysis of recetors for IgA on human polymorphonuclear cells and monocytes and their correlation of receptor expression with phagocytosis. Molec Immunol ; 20 : — IgA-mediated effector function of HL cells following treatment with calcitriol.
Mol Immunol ; 23 : — Antibody-dependent cell-mediated antibacterial activity of human mononuclear cells. K lymphocytes and monocytes are effective against meningococci in cooperation with human immune sera. Colostral mononuclear phagocytes are able to kill enteropathogenic Escherichia coli opsonized with colostral IgA. Scand J Immunol ; 46 : 59 — Parasite Immunol ; 15 : — IgA- and secretory IgA-opsonized S.
ocacudabebus.cf Immunology ; 61 : — IgM monoclonal antibodies recognizing Fc alpha R but not Fc gamma RIII trigger a respiratory burst in neutrophils although both trigger an increase in intracellular calcium levels and degranulation. Immunology ; 86 : 1 —5. Immunoglobulin-A and interleukin 6 form a positive secretory feedback loop: A study of normal subjects and alcoholic cirrhosis.
Gastroenterology ; : — Hepatology ; 13 : — J Infect Dis ; : 82 — IgA-induced eosinophil degranulation. Secretory IgA induces degranulation of ILprimed basophils. Human serum IgA downregulates the release of inflammatory cytokines tumor necrosis factor-alpha, interleukin-6 in human monocytes.
Blood ; 83 : — Activation of guinea pig alternative complement pathway by mouse IgA immune complexes. Inhibition of receptor-dependent and receptor-independent generation of the respiratory burst in human neutrophils and monocytes by human serum IgA. Pediatr Res ; 36 : — Weiner HL. Oral tolerance, an active immunologic process mediated by multiple mechanisms.